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Tec kinases: modulators of lymphocyte signaling and development
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Tec kinases: modulators of lymphocyte signaling and development

Carol M Lewis, Christine Broussard, Michael J Czar and Pamela L Schwartzberg
Current Opinion in Immunology, Vol.13(3), pp.317-325
2001
DOI: https://doi.org/10.1016/S0952-7915(00)00221-1
PMID: 11406363

Abstract

development kinase lymphocyte signaling Tec
The Tec kinases are implicated as important components of the antigen receptor signaling required for proper lymphocyte activation and development. Recent data suggest that these kinases contribute to multiprotein complexes containing LAT and SLP-76 in T cells, and BLNK/SLP-65 in B cells, which are required for activation of PLC-γ and downstream pathways.
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